Headaches, whether they are tension headaches or migraine headaches, muscle cramps and low energy levels, are conditions that can be related to magnesium deficiency. Weak bones and weak muscles are also signs of magnesium deficiency because magnesium is a significant building block of the muscles and bones. Not being able to sleep at night, struggling with anxiety and depression, muscle pain, and constipation can be connected to magnesium deficiency as well. High blood pressure can be a result of not having enough magnesium in the body. Magnesium is one of the best natural remedies to naturally lower or balance out blood pressure.